大部分染色體異常是單一染色體異常(45 or 47染色體)

大部分染色體異常是單一染色體異常(45  or 47染色體)
 
45染色體異常 多於 47染色體異常
 
較多染色體異常來源母系染色體
 
大部分單一染色體異常源自受孕之前之減數分裂異常
 
3個染色體aneuploidy源自受孕後有絲分裂異常
 
母系染色體異常多源自減數分裂
 
父系染色體異常多源自有絲分裂
 
 
 
Single aneuploidy was the most common type in both D3 and D5/6 embryos
 
a prevalence of single monosomy over single trisomy (n = 408, P < 0.0001, binomial test) in cleavage embryos
 
the parental origin of aneuploidy was mainly maternal, demonstrating at least a 2-fold increase in the number of affected maternal chromosomes in both monosomies and trisomies 
 
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