新鮮卵子授精相比，凍卵解凍後進行卵胞漿內精子注射會導致胚胎受孕率降低
新鮮卵子授精相比，凍卵解凍後進行卵胞漿內精子注射會導致胚胎受孕率降低，胚胎品質下降，囊胚形成率較低。但鮮胚植入之懷孕率最低
新鮮卵子授精形成胚胎冷凍再解凍植入懷孕率>卵子冷凍再解凍受孕形成胚胎再植入懷孕率>鮮卵子胚
冷凍卵子不論是在受精率(80% vs 85%)、培養至第三天優質胚胎(31% vs 39%) 或是第五天囊胚發育率(36% vs 41%) 都遜於新鮮卵子。
Freeze-all, oocyte vitrification, or fresh embryo transfer? Lessons from an egg-sharing donation program
Fertil Steril 2016;106:615–22. 2016
◉ Decreased embryo quality and lower rates of blastocyst formation were observed among embryos derived from vitrified oocytes.
◉ The highest pregnancy and implantation rates were noted for the Thaw Cycles Group, followed by the Banked Donor Egg Group;
◉ the Fresh Cycles Group had the lowest rates.
◉ Conclusion(s): Oocyte vitrification followed by intracytoplasmic sperm injection leads to lower embryo developmental competence compared with when fresh insemination methods are used.
◉ However, pregnancy and implantation rates are higher when embryos are transferred into a ‘‘more receptive’’ endometrium, free of the adverse effects of gonadotropin.