自然週期vs誘導排卵

自然週期vs誘導排卵      誘導排卵並不明顯提高胚胎染色體異常率 
自然週期vs誘導排卵      胚胎異常率均隨女性年齡而增加, 
自然週期vs誘導排卵      整倍體囊胚的植入率相同。
誘導排卵對胚胎非整倍體風險或胚胎生殖潛力沒有明顯副作用。
Embryonic aneuploidy rates are equivalent in natural cycles and gonadotropin-stimulated cycles
Aneuploidy rates were equivalent in unstimulated and stimulated IVF cycles. 
The prevalence of aneuploidy in natural cycles increased with the age of the female partner in a manner identical to that seen in stimulated IVF cycles. 
Implantation rates of euploid blastocysts were equivalent in natural and stimulated IVF cycles.
No measurable toxic effect of gonadotropin administration on aneuploidy risk or embryonic reproductive potential. 
 
 
The overall sustained implantation rate (SIR) did not differ for patients in the natural cycle group (60.0%) as compared to superovulatory controls (63.8%)
Patients less than 35 years of age had an SIR of 61.7% in the natural cycle group versus 66.5% in the control group (P=.45). 
There were no differences in SIR between patients that were 35 to 37 years of age in natural cycle (53.3%) versus gonadotropin control cycle patients (62.9%, P=.52). 
Patients between the ages of 38 and 40 had SIR of 69.2% and 60.2%, in study and control groups, respectively (P=.65). 
The SIR similarly did not vary for patients ages 41–42 in the natural cycle group and the superovulatory control group (33.3% vs. 61.4%, P=.33), or greater than 42 years of age (50.0% vs. 50.0%, P>.99). 
 
TOP